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План на курса
Introduction to NGS and Forensic Applications
- Overview of DNA sequencing technologies
- Advantages of NGS over traditional forensic methods
- Common forensic applications of NGS
Fundamentals of Forensic Genetics
- DNA markers used in forensic analysis
- Short Tandem Repeats (STRs) and Single Nucleotide Polymorphisms (SNPs)
- Mitochondrial DNA and Y-chromosome analysis
NGS Workflows in Forensic Casework
- Sample preparation and library construction
- Sequencing protocols for forensic samples
- Quality control and contamination prevention
Bioinformatics and NGS Data Analysis
- NGS data processing and alignment
- Variant calling and forensic interpretation
- Software tools for forensic genomic analysis
Forensic Anthropology and Ancestry Determination
- Genetic markers for ancestry and population studies
- NGS applications in ancient and degraded DNA analysis
- Case studies in forensic anthropology
NGS for Challenging and Degraded Samples
- Techniques for low-quality and low-quantity DNA
- Dealing with environmental and mixed DNA samples
- NGS applications in missing persons and disaster victim identification
Legal, Ethical, and Regulatory Considerations
- Privacy concerns in forensic genomics
- Regulatory frameworks for forensic DNA databases
- Ethical challenges in forensic genetic analysis
Future Trends in Forensic Genomics
- Advancements in sequencing technology
- Integration of AI in forensic genetics
- Emerging forensic applications of NGS
Summary and Next Steps
Изисквания
- Basic knowledge of genetics and forensic science
- Familiarity with DNA sequencing concepts
Audience
- Forensic scientists and geneticists
- Anthropologists and bioarchaeologists
- Law enforcement and forensic investigators
14 Часа
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Още упражнения с нашите последователности
Maria-Adina Gatea - Institutul National de Sanatate Publica
Курс - Basics of Bioinformatics
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